CATO News

CATO's Azithromycin-D5: Powering Precision Analytics

Azithromycin-D5 is synthesized by selectively replacing five specific hydrogen atoms in the azithromycin molecular structure with deuterium. It retains identical chemical properties while exhibiting distinct mass spectrometric characteristics.

Recommended Major Nitrosamine Impurities : N-Nitroso Finerenone

In recent years, drug safety issues have received significant attention. Among these, nitrosamine impurities have become a "Sword of Damocles" hanging over pharmaceutical companies. On March 28, 2025, the FDA updated its "Nitrosamine Impurities Acceptable Intake Limits" database. This update primarily added and adjusted acceptable intake limits for multiple nitrosamine impurities and expanded the substance categories determined by the prediction-based carcinogenic potency classification approach (CPCA), further strengthening drug safety regulations.

CATO Attend 75th PITTCON Conference and Exposition

From February 24-28, 2024, the 2024 Pittcon Analytical Chemistry and Spectroscopy Applications Conference and Exhibition will be held at the San Diego Convention Center.

Representative of fully synthetic fluorocyclines: Eravacycline – Structure, synthesis process, and key points of quality research

Representative of fully synthetic fluorocyclines: Eravacycli

2026 Nobel Prize in Chemistry Awarded to "Left and Right Hands": Why the Same Molecule Has Vastly Different Drug Efficacy

2026 Nobel Prize in Chemistry Awarded to "Left and Right Han

Indapamide: A Technical Review — From Synthetic-Route Impurities to the New Nitrosamine Regulatory Landscape

Overcoming the Three-Disulfide-Bond Purification Barrier: Linaclotide Impurity Profiling and Deficiency Response Strategies

Overcoming the Three-Disulfide-Bond Purification Barrier: Li

Impurity spectrum analysis of Tenofovir Disoproxil: selection of seven major categories of impurities and reference substances

Tenofovir Disoproxil (CAS 201341-05-1), a nucleotide drug that changes the landscape of antiviral treatment, is a nucleotide reverse transcriptase inhibitor (NtRTI) developed by the American company Gilead. It is one of the few approved for HIV (Human Immunodeficiency

Lidocaine Impurity Profile: Genotoxic Aniline Impurity and NDSRI Risk Under Control

Now Available | CATO Acyclovir EP Impurity R – Empowering Antiviral Drug Quality Control

To support quality research and registration submissions, CATO's in-house developed Impurity R reference standard features high purity and high stability, complete with comprehensive Certificate of Analysis (COA), making it widely applicable for process optimization, method development, registration dossier preparation, and various other application requirements.